Your doctor may recommend bio-engineered skin graft or substitutes to help cover a chronic wound – a wound that fails to heal itself within a specific time period. There are different ways to manage chronic wounds, including the use of specialized dressings, surgery like skin flaps and grafts from the patient’s own body, or bio-engineered skin grafts.
Bioengineered skin grafts comprise an outer epidermal layer and a dermal layer embedded into a support structure (acellular matrix) to create a biological skin substitute.
Skin grafts can be derived from human or non-human tissue. Bio-engineered skin grafts are derived either from human placenta (EpiFix® or Grafix®), neonatal foreskin (Dermagraft® or Apligraf®) or porcine stomach lining (Oasis®).
Most of the bio-engineered skin grafts are produced commercially and grown from neonatal (allogeneic) foreskin. This skin graft is preferred because:
Bioengineered skin graft is intended to temporarily assume the role of the epidermis/dermis until the patient’s skin self-repairs or until a definite skin replacement is obtained with a skin graft or some other cultured equivalent.
Research suggests that bioengineered skin grafts hastens the wound healing process by introducing living cells to restore the necessary conditions for repair, including structural support, a moist wound environment, and growth factors (including cytokines) that stimulate natural immune response and foster tissue regeneration.
Here are some of the advantages of using bioengineered skin grafts:
Skin substitutes are known to help reduce pain, close wounds, and promote healing, plus they eliminate the need for surgical skin grafts. Their use has been evaluated for a range of conditions, including:
Studies suggest that bioengineered skin grafting is safe for the above procedures, or at least as safe as the standard therapies used for wound care and burns. Different bio-engineered skin substitutes are labeled for specific uses, and your provider applies them accordingly.
For more information on our bioengineered skin graft substitutes, please call our office @ 1.844.77.VEINS or contact us online here.
Dr. Haimesh Shah of Center for Vein Wellness offers skin substitutes using bioengineered skin graft to patients located in Los Angeles, Ventura, Oxnard, Camarillo, Simi Valley, Thousand Oaks & more.
Everyone here has made me feel like more than just a patient. They are all so nice and I have felt confident that everything is necessary and will make it better. I was lucky enough to meet Dr Shaw at the wound care at pleasant Valley Hospitol where he not only healed my elbow, but noticed he could- Cindy G
2017-07-12- Alfonso G
2017-07-10Es una persona muy amable y muy cuidadoso en su trabajo, y el personal que trabaja con el es muy profesional, me siento cómoda y segura cuando yo tengo que ir alguna cita.- Helena G
2017-06-26Very professional staff- Teresita D
2017-07-03- Manal A
2017-07-28Excelente- Gilberto P
Ventura Location2991 Loma Vista Rd., Suite A103
Ventura, CA 93003
Oxnard Location300 South A Street, Suite A107
Oxnard, CA 93030
Camarillo Location2460 N. Ponderosa Dr., Suite A101
Camarillo, CA 93010
Simi Valley125 Parrot Ln.
Simi Valley, CA 93065
Thousand Oaks415 Rolling Oaks Dr., Suite 250
Thousand Oaks, CA 91361
Palmdale41210 11th St W, Suite E
Palmdale, CA 93551